Termini is the main railway station in the Italian capital and one of the biggest in Europe, with connections all over the continent. If you pick up a hire car here you'll find that the station stands in the central Termini district and forms part of a communications hub for the city: the bus station is next door and the centre of the Metro system is here too. Rome's road system is famously complex but Termini's road connections are as good as it gets: the end of the A24 motorway and the city's ring road are very close by.
Before you leave the Termini Station note its monumental post-war architecture, particularly the high roofed great lobby. Characteristically for the Eternal City there's a section of the Roman city walls right outside the station. If you pick up a hire car here you'll find that this is Rome's main hotel district. It's a maze of busy streets lined with restaurants, markets and quirky shops. Nearby is the busy Piazza della Repubblica, a grand public space with the enormous striking Church of Santa Maria Maggiore, which dates back to the fifth century and Baths of Diocletian, the sumptuous imperial bath-house.